Simultaneous determination and method validation of ranitidine hydrochloride and itopride hydrochloride by UV-spectrophotometery
نویسندگان
چکیده
منابع مشابه
Stability-Indicating LC Method for Simultaneous Estimation of Rabeprazole Sodium Hydrochloride and Itopride Hydrochloride in Combined Dosage Form
A simple, sensitive and precise stability indicating HPLC method has been developed for the estimation of rabeprazole and itopride in combined dosage form. A Phenomenex Gemini C-18, 5 μm column with a mobile phase containing 0.02 M ammonium acetate (pH 6): acetonitrile: methanol (45: 20: 35, v/v/v) was used. The flow rate was 1.0 mL min and effluents were monitored at 284 nm. Rabeprazole and it...
متن کاملDevelopment and validation of a UV spectrophotometric method for the simultaneous determination of ciprofloxacin hydrochloride and metronidazole in binary mixture
A new, simple, accurate and sensitive UV spectrophotometric method was adopted and validated for the quantitative determination of ciprofloxacin hydrochloride (CIP) and metronidazole (MET), simultaneously, either in pure form or in pharmaceutical dosage form. Second derivative ratio spectrophotometry technique (DD) was applied, by measuring the amplitude of the maximum at 253 nm, using a normal...
متن کاملSimultaneous HPTLC Determination of Rabeprazole and Itopride Hydrochloride From Their Combined Dosage Form
A simple, precise, sensitive, rapid and reproducible HPTLC method for the simultaneous estimation of the rabeprazole and itopride hydrochloride in tablets was developed and validated. This method involves separation of the components by TLC on precoated silica gel G60F254 plate with solvent system of n-butanol, toluene and ammonia (8.5:0.5:1 v/v/v) and detection was carried out densitometricall...
متن کاملDetermination of Ranitidine Hydrochloride in Pharmaceutical Preparations by Direct Potentiometriy
A direct potentiometric titration method was applied for determination of Ranitidine Hydrochloride. The method is based on the treatment of the primary data with nonlinear regression procedure using commercial software. A general formula valid for every type of acid base titration, derived before is used as a direct input. The acid-base constants of N, N dimethyl-5 [2-(1-methylamine-2-nitroviny...
متن کاملSimultaneous determination of nortriptyline hydrochloride and fluphenazine hydrochloride in microgram quantities from low dosage forms by liquid chromatography–UV detection
A novel method for the simultaneous high-performance liquid chromatographic determination of nortriptyline hydrochloride and fluphenazine hydrochloride was developed and validated. Fluvastatin sodium was used as internal standard. The determination was performed on a Hypersil Gold C8 column (250 mm × 4.6 mm i.d., 5 μm particle size) at 25 °C; the mobile phase, consisting of a mixture of formic ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: African Journal of Pharmacy and Pharmacology
سال: 2015
ISSN: 1996-0816
DOI: 10.5897/ajpp2015.4379